With these two teams seventh in west and sixth in the east, this cross-conference affair in Utah is vitally important for both.
It’s not been a good week for Real Salt Lake, first held to a goalless draw by D.C. United, before being hammered 3-0 in Austin on Wednesday.
So, Pablo Mastroeni’s side have yielded just one point from their last three outings, despite being unbeaten in four beforehand.
RSL’s final two games are against fellow play-off contenders in the west, namely LA Galaxy and Portland, so every point counts.
In contrast, FC Cincinnati will make the long 1,656 mile cross-country journey brimming with belief, after recording their biggest-ever victory last weekend.
Brenner bagged a hat-trick while Álvaro Barreal, Luciano Acosta and Yūya Kubo were also on target in a 6-0 demolition of San Jose at TQL Stadium.
That is Cincinnati’s sixth home victory of the season, more than they managed in their first three MLS campaigns combined.
To further underline the improvement Pat Noonan has overseen, his team have only lost one of their last 16.
However, with 11 of those matches ending in draws, Cincinnati still have work to do to make the play-offs for the very first time.
Will there be a winner at the recently renamed America First Field?