Six of the last seven meetings between these two have produced home wins, three apiece. None of their last 12 encounters have produced away victories, dating back to a 2-1 Union victory in Ohio six years ago. Columbus Crew have conceded first in each of their last four MLS matches.
Philadelphia to be the first team to score is 4/6.
Both teams to score and over 2.5 goals is 11/10.
Philadelphia Union to win and over 2.5 goals is 2/1.
Dániel Gazdag is 5/1 to break the deadlock and 15/8 to score for the fifth week running.
Philadelphia Union are currently top of the Eastern Conference, but will they stay there come the end of this weekend?
Last time out, Jim Curtin's men beat Charlotte 2-0 with Julián Carranza opening the scoring before Dániel Gazdag pounced on some very slack defending.
This means the Union have won four straight matches since being held to a 1-1 draw by Minnesota Union on the opening weekend.
Philadelphia lifted the Supporters' Shield in 2020 before finishing second in the east and reaching the Conference Finals last season.
Once again, the side from Pennsylvania look like strong contenders.
Columbus Crew meantime were beaten for the first time in 2022 last weekend with Nashville SC leaving Lower.com Field with a 1-0 victory.
Before this, Caleb Porter's side had accumulated eight points from four games, beating two Canadian clubs, Vancouver and Toronto, both at home.
However, the Crew have actually only won one away game since July, form they'll need to address if they're to remain in a play-off position.
Will the Union be too strong at Subaru Park?
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