Given that, at the half-way mark, all four teams in Group F are on four points, it’s very much all to play for.
Last Thursday, these two played out a goalless draw at Liebenauer Stadium; Jusuf Gazibegović sent off late on for the hosts.
Will there be anything to separate them in the Eternal City?
Lazio won their only home game so far, demolishing Feyenoord 4-2, but were then hammered 5-1 by Midtjylland a week later.
I Biancocelesti haven’t finished top of a UEFA group since 2017 but, led by 2019 Europa League winner Maurizio Sarri, are hopeful of changing that.
Similarly, Sturm Graz won 1-0 when Midtjylland visited Austria, before a 6-0 spanking in Rotterdam.
All three of die Schwoazn’s group stage appearances since 2000 have resulted in them finishing bottom, a fact Christian Ilzer’s team are desperate to change.
Here, Lazio are likely to be too strong at Stadio Olimpico.