Tottenham have won four of their last seven matches to nil.
Spurs are enjoying a strong run of form at the moment and should be too strong for Brighton.
The Seagulls have lost six of their last eight matches, including against Spurs in the reverse fixture.
Kane and Son have both been on fire this season scoring a combined total of 29 league goals.
Son netted a hat-trick in his last outing and he now has six in his last three games.
Kane has failed to score in his last three appearances although Saturday's match could be the perfect chance to return to the scoresheet.
Match preview: Tottenham Hotspur vs Brighton & Hove Albion
Tottenham Hotspur opened a three-point gap over Arsenal in 4th with a win over Aston Villa.
Spurs produced a big win at Villa Park as they won 4-0 with Son getting a hat-trick and Kulusevski also finding the back of the net.
Conte's team have now won six of their last seven matches to boost their top-four hopes.
The north London's side front three has been on fire over recent producing a combined total of 35 goal involvements in their last nine matches.
They defeated Brighton 2-0 at the Amex last month with Romero and Kane getting the goals.
Brighton & Hove Albion stun Arsenal
Brighton emphatically ended a run of seven games without a win as they stunned Arsenal in north London.
The Seagulls won 2-1 at the Emirates with Trossard and Mwepu scoring the goals.
Graham Potter's headed into the clash of six straight wins followed by a goalless draw with Norwich.
The win lifts them back into 11th place and level on points with a place in the top half.
Tottenham Hotspur team news
Tottenham have suffered a big blow losing Matt Doherty for the final few matches.
The defender has suffered an MCL injury and is out for around 8 weeks.
He joins Japhet Tanganga and Oliver Skipp on the sidelines.
Brighton & Hove Albion team news
Adam Webster is back in line to start for the Seagulls after returning to the bench against Arsenal.
Meanwhile, Jakub Moder remains sidelined for the rest of the season after undergoing successful knee surgery.
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