Chelsea to win 1-0 (8/1 with Bet365)
Chelsea suffered a worrying 4-1 defeat at the hands of Brentford before also being put to the sword by Real Madrid.
However, the Blues face a struggling Southampton side who are winless in four.
Thomas Tuchel's side have managed to score just once in both their last two league outings.
Kai Havertz to score anytime (5/1 with 888Bet)
Havertz has been Chelsea’s main man over recent weeks replacing Lukaku in the line-up.
He is starting to hit top form having found the back of the net several times over recent weeks.
The German has netted four in his last four league appearances, he also scored again on Wednesday against Real Madrid.
Match preview: Southampton vs Chelsea
Southampton's form has started to curtail over recent weeks.
The Saints have now gone four games without a win and have lost three of those matches.
Ralph Hasenhüttl's side were held to a 1-1 draw with Leeds on the weekend.
James Ward-Prowse netted another stunning free-kick to earn Southampton a point.
They head into Saturday's clash sat 12th in the table but are just a point off the top half.
Chelsea battered by Real Madrid
Chelsea are on the verge of being eliminated from the Champions League after their first-leg defeat to Real Madrid.
The Blues were beaten 3-1 as Karim Benzema netted a hat-trick for Los Blancos.
Thomas Tuchel's side now have a mountain to climb in next week's tie at the Bernabeu.
The defeat to Real followed another battering at Stamford Bridge in which Chelsea lost 4-1 against Brentford.
The Bees stunned their west London rivals as they ran riot at the Bridge.
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