Man City to win and under 2.5 goals (3/1)
Given the nature of the derby and the importance for both, this is likely to be a cagey affair.
Manchester City will desperately need to match or better Liverpool's result when they face West Ham the day earlier.
Manchester United were very poor in their last league outing as they were held to a goalless draw with Watford.
Raheem Sterling to score first (5/1)
Sterling is expected to return to City's line-up having been rested in the FA Cup.
The winger has been a key part of Guardiola's side this season.
He has 13 goals to his name this season.
Match preview: Manchester City vs Manchester United
Manchester City maintained their six-point lead at the top of the table last Saturday with a win at Goodison Park.
Pep Guardiola's side won 1-0 against Everton with Phil Foden scoring the only goal.
They are now six points above Liverpool, but the Reds have a game in hand over them.
City were also in FA Cup action this week as they defeated Peterborough to reach the quarter-finals.
Manchester United held by Watford
Manchester United were held to a goalless draw with Watford last weekend.
The Hornets claimed a huge point at Old Trafford to dent the Red Devils' top four hopes.
Man United are now 4th place but have Spurs and Arsenal hot on their heels.
Manchester City team news
Ruben Dias is a doubt for the match after suffering a leg injury.
Zack Steffen and Cole Plamer both remain sidelined.
Manchester United team news
Scott McTominay is back from an illness.
Edinson Cavani is still out due to a groin problem.
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