Given the nature of the derby and the importance for both, this is likely to be a cagey affair.
Manchester City will desperately need to match or better Liverpool’s result when they face West Ham the day earlier.
Manchester United were very poor in their last league outing as they were held to a goalless draw with Watford.
Sterling is expected to return to City’s line-up having been rested in the FA Cup.
The winger has been a key part of Guardiola’s side this season.
He has 13 goals to his name this season.
Match preview: Manchester City vs Manchester United
Manchester City maintained their six-point lead at the top of the table last Saturday with a win at Goodison Park.
Pep Guardiola’s side won 1-0 against Everton with Phil Foden scoring the only goal.
They are now six points above Liverpool, but the Reds have a game in hand over them.
City were also in FA Cup action this week as they defeated Peterborough to reach the quarter-finals.
Manchester United held by Watford
Manchester United were held to a goalless draw with Watford last weekend.
The Hornets claimed a huge point at Old Trafford to dent the Red Devils’ top four hopes.
Man United are now 4th place but have Spurs and Arsenal hot on their heels.
Manchester City team news
Ruben Dias is a doubt for the match after suffering a leg injury.
Zack Steffen and Cole Plamer both remain sidelined.
Manchester United team news
Scott McTominay is back from an illness.
Edinson Cavani is still out due to a groin problem.
Manchester City vs Aston Villa - 3:2
West Ham United vs Manchester City - 2:2
Wolverhampton Wanderers vs Manchester City - 1:5
Manchester City vs Newcastle United - 5:0
Real Madrid vs Manchester City - 3:1
|Latest match form, last 5 games:||
Crystal Palace vs Manchester United - 1:0
Brighton & Hove Albion vs Manchester United - 4:0
Manchester United vs Brentford FC - 3:0
Manchester United vs Chelsea FC - 1:1
Arsenal FC vs Manchester United - 3:1
|May 22, 2022||Premier League 21/22||Manchester City||3 - 2||Aston Villa|
|May 15, 2022||Premier League 21/22||West Ham United||2 - 2||Manchester City|
|May 11, 2022||Premier League 21/22||Wolverhampton Wanderers||1 - 5||Manchester City|
|May 8, 2022||Premier League 21/22||Manchester City||5 - 0||Newcastle United|
|May 4, 2022||UEFA Champions League 21/22||Real Madrid||3 - 1||Manchester City|
|May 22, 2022||Premier League 21/22||Crystal Palace||1 - 0||Manchester United|
|May 7, 2022||Premier League 21/22||Brighton & Hove Albion||4 - 0||Manchester United|
|May 2, 2022||Premier League 21/22||Manchester United||3 - 0||Brentford FC|
|April 28, 2022||Premier League 21/22||Manchester United||1 - 1||Chelsea FC|
|April 23, 2022||Premier League 21/22||Arsenal FC||3 - 1||Manchester United|
|Manchester City||Manchester United|
|241||Shots on goal||190|
|216||Shots off goal||163|
|69%||Average ball possession||52%|
|4||Shots on post||4|
|3||Shots on bar||2|
|82||Goals by foot||50|
|14||Goals by head||6|
|Manchester City||Manchester United|
|1.32||Average Goals Scored||1.25|
|March 6, 2022||Premier League 21/22||Manchester City||4 - 1||Manchester United|
|November 6, 2021||Premier League 21/22||Manchester United||0 - 2||Manchester City|
|March 7, 2021||Premier League 20/21||Manchester City||0 - 2||Manchester United|
|January 6, 2021||EFL Cup 20/21||Manchester United||0 - 2||Manchester City|
|December 12, 2020||Premier League 20/21||Manchester United||0 - 0||Manchester City|
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What time is kick off between Manchester City vs Manchester United?
16:30, Sunday 06 March 2022