Two teams, dangerously close to the relegation zone, go head-to-head in South London.
Southampton are looking to extend their unbeaten streak to four matches, claiming their first win since August at Bournemouth ten days ago.
Either side, the Saints have earned a pair of 1-1 home draws, first with West Ham and then against Arsenal on Sunday.
Stuart Armstrong rounding off an excellent team move last weekend to help his team take a point.
Ralph Hasenhüttl’s side are still just two places and three points clear of danger, but are targeting back-to-back away wins for the first time since June 2020.
Crystal Palace meanwhile were surprisingly hammered 3-0 at Goodison Park by Everton a week ago.
Prior to this, Patrick Vieira’s team were unbeaten in three, beating both Leeds and Wolves, drawing at Leicester in-between.
So, the Eagles are in 13th place, aiming for a third consecutive home win, last achieve that in April 2018.
Who will prevail at Selhurst Park?
Crystal Palace team news
Cheick Doucouré missed the trip to Everton due to suspension, but will return at the base of midfield, with Luka Milivojević making way.
Centre-back Marc Guéhi is now one booking away from a ban of his own.
Aside from Doucouré, the XI is likely to remain unchanged, with Odsonne Édouard leading the line.
Wilfried Zaha has scored four goals in last seven Premier League appearances against Southampton.
Southampton team news
Right-back was Ralph Hasenhüttl’s biggest concern last weekend, with Kyle Walker-Peters joining Tino Livramento in the treatment room.
Lyanco filled in there, but Ainsley Maitland-Niles, who was ineligible against Arsenal, is likely to do so here.
With Armel Bella-Kotchap sidelined due to a shoulder injury, Duje Ćaleta-Car will continue to partner Mohamed Salisu at centre-back.
Captain James Ward-Prowse has scored three times against Palace, including a stunning free-kick at Selhurst last December.