Real Sociedad have won just two of their last 16 meetings with Real in Madrid, but those victories came in 2019 and 2020, the latter 4-3 in the Copa del Rey en route to lifting the trophy. Los Blancos are unbeaten in 26 La Liga matches at the Bernabéu.
Real Madrid to win and both teams to score NO is 13/8.
Karim Benzema is 11/4 to break the deadlock and 4/5 to add to his tally.
Will Real Madrid maintain their six-point lead at the top of La Liga?
Last weekend, los Blancos battled to a narrow, nervy 1-0 victory over city-rivals Rayo Vallecano at Campo de Fútbol de Vallecas.
Thibaut Courtois was man of the match, making a string of fantastic saves, but Karim Benzema, who else, got the only goal just seven minutes from time.
This means, despite only winning four of their last seven La Liga games, Carlo Ancelotti's side remain six points clear of Sevilla.
Given that Sevilla face Alavés on Friday night, that gap may have been halved by the time this one kicks off, making a home win all the more important.
Despite the fact Paris Saint-Germain are visiting the Spanish capital on Wednesday, Real Madrid cannot take their foot off the gas in this one.
Real Sociedad meanwhile make the 281 mile journey south in confident mood after back-to-back wins this week.
Imanol Alguacil's side beat Osasuna 1-0 last Sunday before winning again on Wednesday, this time 2-0 at Son Moix against RCD Mallorca.
David Silva and then Mikel Merino on target in Palma.
Prior to this, La Real had been dumped out the Europa League and suffered their biggest Basque Derby defeat for 63 years, losing 4-0 to Athletic.
So, having won back-to-back league games for the first time since 26 September, los Txuri-Urdin are now sixth, just one point below the top four places.
Can they now cause a huge upset at Estadio Santiago Bernabéu?
Real Madrid team news
Carlo Ancelotti, famously, only really trusts ten first-team players so very rarely rotates his squad.
After a free week, this is likely to remain the case.
The only positition that was up for grabs earlier in the season was right-wing but Marco Asensio has seemingly nailed down that positition.
Isco, Gareth Bale, Eden Hazard, Rodrygo and Luka Jović have all be struggling for minutes for a very long time.
Elsewhere, David Alaba missed the win over Rayo but is hoping to return at centre-back, taking Nacho's place.
Karim Benzema and Vinícius Júnior remain the main goal threats having now scored 26 and 16 goals respectively this season.
Real Sociedad team news
La Real are without Nacho Monreal, Ander Barrenetxea and Carlos Fernández due to injury.
However, Alexander Isak is back and that is a major boost, even if the Swedish international was an unused substitute against Mallorca.
But, he'll surely return here, in place of Alexander Sørloth, with David Silva and Mikel Oyarzabal in support.
Álex Remiro will continue in goal, despite some shaky performances, with Mat Ryan still on the bench.
La Liga table:
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