Can Real Madrid close the gap at the top, before their title-rivals are in action 24 hours later?
On Wednesday night, los Blancos smashed bottom of the table Elche 4-0, with Marco Asensio, Karim Benzema and Luka Modrić all on target at the Bernabéu.
However, having only won five of their last ten La Liga fixtures, Carlo Ancelotti’s team remain eight points adrift run-away leaders Barcelona.
This forthcoming Tuesday, los Merengues will take on Liverpool at Anfield in the first leg of their Champions League round of 16 tie.
Before that huge trip to England, Real Madrid will certainly be in for a tough game here.
Osasuna have only lost four of 11 home matches this season, and start the weekend ninth, despite a recent down-turn in form.
Jagoba Arrasate’s team are winless in four, albeit three of these games have been draws, but this has somewhat derailed los Rojillos’ European aspirations.
Nevertheless, Real Madrid are unlikely to cruise to victory at El Sadar, which is La Liga’s classic ‘tough place to go’.