Both of these clubs needed replays in round three, so will this on end in a draw too?
Leeds United very nearly exited the competition against Cardiff City, coming from 2-0 down to salvage a draw in South Wales.
Rodrigo halving the deficit in that one, before 18 year old Sonny Perkins snatched a dramatic stoppage time equaliser.
Nine days later, Leeds demolished Cardiff at Elland Road, racing into a 5-0 lead, eventually prevailing 5-2, with both Wilfried Gnonto and Patrick Bamford bagging braces.
Prior to this, the Whites had fallen in round three in five consecutive seasons, last featuring in the quarter-finals two decades ago.
Meanwhile, in the Premier League, Jesse Marsch’s men are finding victories hard to come by, winning just two of their last 16.
In fairness, three of their last four have ended all square, including Sunday’s goalless stalemate with Brentford.
Before next Sunday’s crucial trip to Nottingham Forest, will the 1972 FA Cup winners march on into round five?
Hosts Accrington Stanley meantime are on the verge of reaching the fifth round for the first time in their 54 year history.
So far, they’ve seen off Crawley, Barnet and then Boreham Wood, prevailing in a replay against the latter as recently as Tuesday night.
After a 1-1 draw at Meadow Park, Tommy Leigh’s penalty, coming in extra time, was enough to, in the end, see off the non-league side.
The ‘Owd Reds are struggling in League One just now, sat 20th, having lost three of their last four, but John Coleman’s team will believe history is possible here.
Will Leeds prove to be too strong at the Crown Ground?
Accrington Stanley team news
Midfielder Seamus Conneely is out injured, but Rosaire Longelo and Aaron Pressley, both of whom came off the bench in mid-week, could be fit to start.
Shaun Whalley has already scored three times in this season’s FA Cup, with only Armando Dobra of Chesterfield and Wrexham’s Paul Mullin having scored more, from round one onwards.
Predicted XI (3-5-2): Savin; Tharme, Astley, Nottingham; Martin, Hamilton, Coyle, Rodgers, McConville; Leigh, Whalley.
Leeds United team news
Striker Georginio Rutter, who’s arrived from Hoffenheim for a club-record £36 million, could make his Leeds debut here.
Luis Sinisterra came off the bench against Brentford, making his first league appearance since 23 October due to a foot injury.
Elsewhere, Joel Robles, Rasmus Kristensen, Junior Firpo and Sam Greenwood could be rotated into the XI, but Crysencio Summerville is a doubt.
Patrick Bamford has scored three goals as a substitute this month, but last started a game in mid-October.
Predicted XI (4-3-3): Joel; Kristensen, Llorente, Wöber, Firpo; Greenwood, Roca, Harrison, Gnonto, Sinisterra; Rutter.