Five of the last nine meetings between these two have produced home wins, including their most recent clash, a 4-0 New England victory in Foxborough three years ago. The Revs have only won one of four visits to Vancouver, leaving 2-1 winners in 2016.
Both teams to score is 8/13.
Draw and both teams to score is 15/4.
Lucas Cavallini is 5/1 to break the deadlock and 7/5 to score in, what will be, his first-ever match against the Revs.
These two sides have had similar seasons; both started slowly, but are now starting to climb up their respective conferences.
For New England Revolution, they came from behind to beat Minnesota United 2-1 in Foxborough last weekend.
Dylan Borrero equalising before Gustavo Bou won it for the Revs with a pin-point free-kick at Gillette Stadium.
So, despite losing five games on the bounce in March/April in all competitions, Bruce Arena's men are now unbeaten in eight, winning four.
This has lifted last season's Supporters' Shield winners up to sixth in the east, looking to cement their place above the play-off line.
Vancouver Whitecaps meanwhile start the weekend below the west's dotted line only due to Seattle's superior goal difference.
However, the Blue-and-White have enjoyed a fantastic week, first beating FC Dallas 2-0 in Frisco last weekend.
Lucas Cavallini breaking the deadlock after just 99 seconds, the Caps' fastest goal for over six years, before Déiber Caicedo's free-kick sealed the win.
This means Vancouver have won two of their last three MLS matches on road, despite only winning two of the previous 29.
Then, on Wednesday the Whitecaps reached the Canadian Championship Final, overcoming York United 2-1 at home.
Brian White scoring a brace, meaning they'll now take on Toronto FC with silverware on the line next month.
In all competitions, Vanni Sartini's team have won eight of their last 11 outings, hoping to continue that form here.
Will there be a winner at BC Place?
- 101 Great Goals may earn commission from links on this page. Our content is always original. Note that all of our reviewers are compensated for contributing content to 101 Great Goals. Learn more.