It is the biggest game of the Premier League season and will likely decide who lifts the title in May.
Arsenal head into the game top of the Premier League by five points. However, Manchester City have two games in hand.
As a result, if City win or draw this tie, they will likely go on to be crowned champions. But if Arsenal win, they will have a two-point lead even if City win their two games in hand.
Here is 101GreatGoals’ combined XI ahead of the game.
Both keepers have been in good form this season, but Ederson has conceded less and Aaron Ramsdale has made a few mistakes of late.
RB: Ben White
Despite being a centre-back by trade, Ben White has been superb at right-back this season. He is solid defensively and has also formed a great partnership with Bukayo Saka down the right-flank.
CB: Ruben Dias
Dias has been one of the most consistent defenders in the PL this term, making some major blocks and tackles to keep City firmly in the title race.
Gabriel’s form has dipped slightly since Rob Holding came into the team but the Brazilian has scored some key goals and won two MOTM awards in 2022/23 for the Gunners.
LB: Oleksandr Zinchenko
Zinchenko had a tough outing vs Southampton on his return from injury last time out but before that the 26-year-old had excelled in his inverted full-back role.
Rodri is arguably the perfect CDM. He links defence and attack with ease and is excellent at stopping opposition counters.
CM: Kevin De Bruyne
De Bruyne is in the midst of another excellent season, having already notched five goals and a staggering 17 assists in 28 league outings.
CM: Martin Odegaard
Whilst the comparisons to KDB earlier in the season were somewhat premature, Odegaard’s creativity is essential to this Arsenal side. He has 12 goals and eight assists in 31 games in 2022/23.
RW: Bukayo Saka
Manchester City have not had a consistent right-winger this season, with none of their current options coming close to Bukayo Saka who has scored 13 and assisted 11 in 32.
ST: Erling Haaland
Erling Haaland has 32 goals and five assists in 28 PL matches this season and is one goal away from scoring the most goals in a 38-game PL campaign.
LW: Gabriel Martinelli
Whilst Jack Grealish has improved in recent months, Martinelli has been one of the deadliest wingers in the prem this year, netting 15 and assisting five in 32.