We will then see Leicester and Crystal Palace clash in Saturday’s early kick-off, before Wolves vs Nottingham Forest and Fulham vs Bournemouth at 3 pm. Saturday’s league action is rounded out by Tottenham vs Everton at 5:30 pm.
There are then five Premier League games on Sunday. Southampton vs West Ham, Manchester United vs Newcastle, Leeds vs Arsenal and Aston Villa all take place at 2 pm, with Liverpool vs Manchester City rounding out the day’s and gameweek’s action.
Here are five talking points ahead of the upcoming gameweek.
End of the Klopp-Pep rivalry
For many years the media attempted to and largely succeeded in fostering the Jurgen Klopp vs Pep Guardiola rivalry.
Liverpool and Manchester City were the two best teams in the Premier League and even if Liverpool only won one title, it was still all about Pep vs Klopp.
Now though, Manchester City are unbeaten in nine and Liverpool are sat down in 10th with just two wins to their name.
A win for City on Sunday will therefore likely put an end to the Klopp vs Pep saga. Arteta vs Pep anyone?
Arsenal march on
Whilst Manchester City remain unbeaten in the league, it is Arsenal who currently sit atop of the Premier League.
The Gunners are on 24 points after winning eight and losing one, with their last outing a win over Liverpool.
They now face a Leeds side who are struggling for form. Can Arsenal keep up their good form and compete with Manchester City?
Chelsea on the up
Whilst a push for the title may be out of the question this season, Chelsea are in fine form under their new boss.
Chelsea’s last four matches have seen them beat Crystal Palace, Wolves and AC Milan twice.
The Blues will now go head-to-head with Steven Gerrard’s Aston Villa, a tie they are expected to win and one that could close the gap on themselves and the top two.
Zak Rodgers, Brenda Nout. Just two of the ‘birthday’ messages that were sent in by fans of Leicester this week that they wanted read out on the big screen during the game.
Leicester are currently dead bottom of the Premier League with four points from nine games.
Their only win has come against fellow struggles Nottingham Forest. A loss vs Crystal Palace on Saturday will likely signal an end to Brendan Rodgers’ time at the King Power.
Battle of the defence
For many, Everton were amongst the favourites to be relegated from the Premier League this season.
However, the Toffees are currently 12th in the table with the joint-best defence in the division.
This gameweek sees them take on Tottenham, who themselves have the joint-second best defence in the league.