There are then a number of games called off over the weekend, but there is still plenty of action to sink your teeth into.
Arsenal face Brentford, Manchester City are in action vs Wolves and Tottenham host Leicester City.
Here are five key talking points ahead of the weekend’s Premier League games.
Kane dominates Leicester
Tottenham take on Leicester City this weekend in Saturday’s late Premier League kick-off.
It is a game Harry Kane is likely very much looking forward to, and not just because Leicester are in poor form.
Kane has scored a staggering 19 goals vs the Foxes in previous meetings, which is the most he has netted vs a single club by some distance – the next being 14 vs Everton.
Can Erling Haaland be stopped?
Erling Haaland is a serious monster and is expected to break a number of Premier League records this season.
The Norwegian is in sensational form at present, providing one assist and 10 goals in six league games so far this term. In the Champions League, meanwhile, he has netted three in two.
Can Wolves finally put a stop to the striker’s superb form?
Brendan Rodgers on the ropes?
With Thomas Tuchel sacked, Brendan Rodgers is now favourite to be the next Premier League managed sacked.
Leicester have not won a single league game so far this season, and currently sit dead bottom of the Premier League with a point to their name and 16 goals conceded.
This is probably not the best time for Leicester to be facing Kane, and with an international break coming up, it may be a good time to move in a different direction.
The only team other than Leicester without a league win this season is Everton.
The Toffees have drawn four matches in 2022/23, but are seriously struggling for goals, netting just four in six – only Wolves and West Ham have scored fewer.
Everton face West Ham on Sunday in what feels like a must-win for both teams.
Can Arsenal bounce back?
Arsenal had a superb start to 2022/23, winning their opening five league games.
However, all of those wins came against newly-promoted teams or sides seriously struggling for form like Leicester and Everton.
And as soon as Arsenal faced a real test in the form of Manchester United, they were beaten. Will the Gunners face a similar fate vs Brentford?