It is another big afternoon for Ruben Amorim and Manchester United.
United have won just one of their last five games in all competitions, and exited the FA Cup to Fulham last weekend.
They were better in drawing 1-1 at Real Sociedad in the Europa League on Thursday night but Amorim has yet to convince he is a significant upgrade on Erik ten Hag.
Arsenal arrive at Old Trafford having all but secured their place in the quarter-finals of the Champions League following Tuesday night’s 7-1 demolition of PSV Eindhoven at the Philips Stadion.
They also need to keep winning in the Premier League in order to capitalise on any slip up from leaders Liverpool.