Liverpool picked up a 4-3 win over Tottenham on Sunday afternoon, which moved them up to 5th in the Premier League.
They are now seven points off Manchester United with one game in hand, meaning they can close that gap to four points with a win on Wednesday.
However, they can still also slip out of the Europa League places as 8th place Brighton are just four points off them with two games in hand.
As for Fulham, they have dropped into midtable after losing three of their last five league matches.
Predicted Liverpool line-up vs Fulham
Liverpool team news vs Fulham
Stefan Bajcetic and Calvin Ramsey are out for the remainder of the campaign with thigh and knee injuries.
Naby Keita and Roberto Firmino both have knocks and are likely to be out of action until the weekend, meaning they will miss out vs Fulham.