Los Angeles Rams @ Seattle Seahawks: Preview, prediction and odds

The Seattle Seahawks and Los Angeles Rams face off in one of the most important games of the 2025 NFL season on Thursday Night Football.

Los Angeles Rams @ Seattle Seahawks: Preview, prediction and odds

Preview for Los Angeles Rams @ Seattle Seahawks

The Seattle Seahawks and Los Angeles Rams face off in a mouthwatering Thursday Night Football clash that will go a long way to determining who finishes the regular season as the number one seed in the NFC.

Seattle and Los Angeles are each 11-3, tied for the second-best record in the NFL, with the Rams holding the tiebreaker in the fight for the NFC West title and top spot in the conference following their narrow victory over the Seahawks in Week 11.

However, a win for the Seahawks would see them take control of the race for the lone first-round bye in the NFC and homefield advantage throughout the playoffs.

Seattle’s offense was frustrated by the Rams’ defense in that 21-19 defeat, with quarterback Sam Darnold’s excellent season interrupted as he was intercepted four times.

The Seahawks’ attack enters this game coming off an underwhelming display in last week’s 18-16 win over the Indianapolis Colts, in which Seattle did not find the endzone, winning behind six Jason Myers field goals.

Seahawks QB Sam Darnold.

Despite the high-powered nature of both offenses, another defensive struggle would be no surprise, especially with Rams wideout Davante Adams doubtful because of knee and hamstring injuries.

His likely absence is a huge blow to Rams quarterback and MVP frontrunner Matthew Stafford, though Darnold will also have to cope without a key player, with left tackle Charles Cross ruled out because of a hamstring issue. Josh Jones is set to deputise.

A factor that could hinder both teams is the weather, with a 90 percent chance of rain forecast in the Seattle area on Thursday evening.

But Stafford is undaunted by the prospect of facing Seattle in such conditions.

“Both teams have to play in it,” he said on Tuesday. “So you just got to adjust as you play.

“You just got to call the game, play the game as the weather allows you to, and for me personally, just try to do everything I can to continue do what I always do, throw it in a good spot and let those guys go make plays.”

Should Stafford and Co. handle the conditions and make enough plays to prevail, it would mark their second sweep of the Seahawks in three seasons, and put them in an excellent position to ensure the road to the Super Bowl in the NFC goes through their SoFi Stadium home.

Prediction for Los Angeles Rams @ Seattle Seahawks

Seahawks

24 19

Rams

The Rams won the first matchup, but on a short week and without one of their top weapons, it’s easy to see Los Angeles slipping up against a ferocious defense and an equally fierce crowd on the road.

Bet Here

How to watch Los Angeles Rams @ Seattle Seahawks

The Los Angeles Rams-Seattle Seahawks matchup kicks off at 8:15pm ET.

It will be broadcast on Amazon Prime Video and simulcast on KTTV (FOX/11) Los Angeles and KCPQ (FOX/13) Seattle.

The game can also be streamed via NFL +.

Best betting offers for Los Angeles Rams @ Seattle Seahawks

If you or someone you know has a gambling problem and wants help, call or visit the Council on Compulsive Gambling:

  • Gamblers Anonymous at 855-2-Call GA or www.gamblersanonymous.org
  • CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV or WY – Call 1-800-GAMBLER
  • AZ- Call 1-800-NEXT-STEP
  • IA – Call 1-800-BETS-OFF
  • KS, NV – Call 1-800-522-4700
  • KY – Call 1-800 GAMBLER, 18+
  • MI – Call 1-800-270-7117 for confidential help
  • MA – Call 1-800-327-5050
  • NC – Call – 1-800-662-4357
  • NY- Call 877-8-HOPENY or text HOPENY (467369)

DISCLAIMER: The information on this site is for entertainment purposes only. Gambling comes with its fair share of risks, and is is important to recognize that when using online gambling sites.

While we review different gambling sites, you should check with local laws in your area before gambling online. Also, all gambling sites and guides are rated 21+ only.

The following free gambling addiction resources can be of help:

21+ Please Gamble Responsibly. Gambling Problem? Call or text 1-800-GAMBLER