Can Real Betis claim a first home league victory since mid-October?
On Wednesday night, Béticos were beaten 2-1 by Barcelona, unable to find an equaliser after Jules Koundé's calamitous late own goal set-up a grand-stand finish.
So, having won just three of their last ten in La Liga, Manuel Pellegrini’s team remain sixth, albeit just three points below Atleti in third.
Celta de Vigo meantime beat Betis 1-0 at Balaídos in September, and would love a repeat of that in Seville.
O Celtiña start the weekend just one point clear of the relegation zone, climbing out of the bottom three by beating Athletic last weekend.
Iago Aspas, who else, the only scorer last Sunday.
Before this, Carlos Carvalhal’s team had won just one of 12 league matches, this coming against rock-bottom Elche.
So, despite their own trials and tribulations, Betis are favourites to win this one at Estadio Benito Villamarín.