Premier League Betting Tips

Southampton vs Liverpool betting tips: Premier League preview, predictions & odds

The Reds have the upper hand in the head to head, with 24 wins to Southampton's 11, from their 45 encounters in the Premier League. Going back to the first competitive match between them in the FA Cup back in 1902, Liverpool’s superiority in the head to head is still apparent with 59 wins to 31 despite losing the first-ever match 4-1. The two clubs didn’t meet in the football league until 1960 when the Saints were 4-1 winners once again.

Liverpool battered Southampton 4-0 at Anfield in the reverse fixture back in November and are the massive favourites to make it a league double here, possibly even by the same scoreline, considering only relegated Watford have picked up fewer points in the last ten games than Southampton's five. Therefore, 101 Great Goals' prediction for this match is Southampton 0 - 4 Liverpool and is available at odds of 18/1.

Alternatively, you can bet on any Southampton win at 7.4/1 against Liverpool at home on Tuesday.

Or, back any away win for Liverpool at 1.33/1 here at the St Mary's Stadium.

You can find odds of 5/1 for any draw between Southampton and Liverpool on Tuesday.

Competition Odds

Liverpool secured a domestic cup double at the weekend beating Chelsea to lift the FA Cup (pictured above) for the first time since 2006. It was the second time this season they had defeated Chelsea, both times on penalties, having previously done so in the League Cup final back in February.

They last won a domestic double in 2001 and added the UEFA Cup to the haul later in May to make it a Cup treble. The Reds are in their third UEFA Champions League Final in five years under Jurgen Klopp. They are the favourites at 2.05/1 to win the UEFA Champions League and make it a Cup treble once again.

Liverpool are also still in with a slim chance of winning the Premier League this season. Although, they will need Steven Gerrard’s Aston Villa to do them a favour and take points off Manchester City in the final match of the season. They are underdogs at 7.5/1 to make it a domestic treble with the Premier League. If you believe they can do the seemingly impossible and become the first side to win the quadruple of Premier League, Champions League, League Cup and FA Cup, odds of 11/1 can be found.

Bet on Southampton vs Liverpool at bet365 by clicking here.

Match preview

Southampton welcomes Liverpool to the St Mary's Stadium on Tuesday for this Premier League match. Following Leeds’ 1-1 draw with Brighton at the weekend, the Saints are now mathematically safe from relegation.

However, there will be concerns internally at the club at Ralph Hasenhüttl’s record of seven defeats in the last ten games. Is this just the players easing off once they felt nothing was left to play for? Or a sign he has lost the dressing room at the club and a fresh face may be needed to get things back on track?

This only raises the question of when to take action. Do you get in someone new in the summer to give them a transfer window and pre-season to build their team and get to work on their ideas? Or, do you give Ralph the transfer window and the start of the new season given the relatively little he has spent to shape his squad?

The four teams occupying the bottom four places in the Premier League right now were all in the bottom five after ten games this season. A bad start can be almost impossible to shake off in this league which makes getting the decision right all the more important for Southampton.

Liverpool will come into this match on a high having won the FA Cup at the weekend. Manchester City’s draw against West Ham also keeps their hopes of winning the Premier League alive going into the final weekend of the season, assuming they win here.

Manchester City’s equaliser in that match essentially rules out the importance of goal difference with it being exceptionally unlikely that Liverpool will collect four points and Manchester City zero from the remaining games. Had City lost to West Ham, a win here would put Liverpool level on points and needing to make up a difference of six goals which could have produced a crazy game with Liverpool going all-out to score as many as possible.

Instead, the task is now a simple one for Jurgen Klopp’s Reds; win your two remaining games and hope City drops points against Villa. Perhaps even more importantly though, avoid any further injuries with another Champions League final on the horizon. They won’t want to be the walking wounded going into that match against Real Madrid with question marks over any further key players.

As a result, we could see a heavily rotated side here with so many players having played 120 minutes plus at the weekend. They say squads win you titles and Tuesday could be the chance for Liverpool’s squad players to keep the Reds’ faint hopes alive in this one.

Sadio Mane Goalscorer - It is crazy to think there were doubts over the value in spending over thirty-million pounds on Sadio Mané (pictured above) when Liverpool signed him from the Saints back in 2016/17. Jamie Carragher admitted recently he had voiced his doubts at the deal when it was announced. However, having won everything there is to win at Liverpool and with the Senegal captain now one of the favourites for this year’s Ballon d’Or, such doubts have not aged well.

Mané has been in white-hot form lately with eight goals in his last eleven starts for Liverpool. The former Saint is 5.5/1 to score the game’s opener on Tuesday. Or 2.3/1 to bag a goal at any time during the game against his former club.

Southampton team news

Valentino Livramento (pictured above) is likely out for the remainder of 2022 with a cruciate ligament injury. The young right-back had been one of the Premier League’s surprise packages this season and there was already talk of the Premier League’s big boys interested in taking him off Southampton’s hands for a hefty fee. Kyle Walker-Peters has switched over from left to right back in his absence with Romain Perraud coming in at left-back for the Saints.

Will Smallbone, Moussa Djenepo, and Theo Walcott were all absent from the squad that travelled to Brentford and lost 3-0 in Southampton’s last match. The trio have all struggled with their fitness this season with just one start between the three of them in the second half of the season. Sixteen-year-old Tyler Dibling was called up to his first Premier League squad against Brentford and was an unused substitute. The highly-rated England under-16 international could get some minutes on the pitch here in what is a dead rubber for the Saints.

Liverpool team news

Liverpool’s FA Cup win on Saturday came at a high cost. The club’s top scorer Mohamed Salah (pictured above) lasted only thirty minutes of the first half before going down with a suspected groin injury. Then their record signing Virgil van Dijk came off at the start of extra time. Virg confirmed in the post-match interview that he felt a small twinge in his knee after just twenty minutes of the match. However, once they reached extra time they agreed the risk was too great to leave him on for a further thirty plus minutes with tired legs.

Neither are likely to be involved here with such a small turnaround time between games coupled with a coming UEFA Champions League final which takes priority. Therefore, they will join Fabinho in the stands who was a mere spectator on Saturday as he rests on a minor hamstring problem. Andrew Robertson is also likely to be rested after being removed with a cramp in extra time with the winning penalty scorer Kostas Tsimikas replacing him. Trent Alexander-Arnold, Jordan Henderson, Thiago and Sadio Mane could also be contenders for a rest having played the full 120 minutes of the match.

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Stephen Drennan

Stephen Drennan

Freelance writer, translator and transcriber. Co-founder of website. Made in Northern Ireland. Specialise in writing in-depth tactical and statistical analysis. I support Liverpool, Real Betis, Sampdoria, Stuttgart, Brazil and Norn Iron!

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