Neither of these two have made ideal starts to the new season, so who will prevail in this Claret clash?
Aston Villa, unlike their visitors, do have three points on the board, these yielded from their only home game to date against Everton.
On the road though, Steven Gerrard’s team have lost both games, first going down 2-0 at Bournemouth and then 3-1 at Crystal Palace.
Last weekend, Ollie Watkins actually gave the Claret and Blue Army a fifth minute lead at Selhurst Park, but to no avail.
Overall, dating back to 10 March, the Villans have won just three of their last 14 Premier League games, leading many to suggest Gerrard is under pressure.
Given this, Tuesday night’s Carabao Cup victory over Bolton Wanderers was much needed.
The League One club actually took an early lead in that tie, only for Douglas Luiz to equalise directly from a corner.
Danny Ings then fired Villa in front from the penalty spot, before Lucas Digne and Leon Bailey sealed the win.
Back in the league and back at home, will Aston Villa claim three vital points?
West Ham United meanwhile are the only team in the Premier League with zero points to their name and are actually yet to score this season.
Last weekend, the Hammers were blunted at the London Stadium, beaten 2-0 by Brighton & Hove Albion.
This followed a lifeless defeat against Manchester City and a ridiculously unlucky 1-0 reverse at Nottingham Forest.
In better news, David Moyes’ side were also in mid-week action, booking their place in the Europa Conference League group stages.
Gianluca Scamacca, Saïd Benrahma and Tomáš Souček were all on target in Denmark in Thursday’s 3-0 victory over Viborg, wrapping up a 6-1 aggregate success in the play-off round.
Last season’s Europa League semi-finalists will be hoping for another extending continental campaign.
Before then, having won their last two visits to Villa Park 3-1 and 4-1, will West Ham win three successive visits to the venue for the first time since 1967?