New York Red Bulls have actually won their last three meetings with San Jose, victorious 5-1, 3-1 and 4-1. The Quakes though had only lost one of their previous ten home games against RBNY before defeat four years ago.
So, both teams to score is 4/5.
Draw and both teams to score is 7/2.
Lewis Morgan is 10/1 to open the scoring and 7/2 to mark his New York debut with a goal.
Jeremy Ebobisse meanwhile is 13/2 to score first and 9/4 to score on his first appearance for San Jose.
Two of Major League Soccer's oldest and most-established clubs kick off in California, hoping for better in 2022.
San Jose Earthquakes won the Supporters' Shield in 2012 but, since then, have qualified for the play-offs just twice in nine campaigns.
Last season, the Quakes finished tenth in the Western Conference, seven points below the play-off line.
Despite this, Matías Almeyda will start his fifth season as manager, certainly aiming for better.
In the off-season, MLS's record goalscorer Chris Wondolowski has retired after 12 seasons with the club, while Florian Jungwirth has left for Vancouver.
In have come Ján Greguš, Jamiro Monteiro and Jeremy Ebobisse, the latter to be their new starting number nine.
Will the post-Wondolowski era begin with a victory?
New York Red Bulls meanwhile have never won MLS Cup but do have three Supporters' Shields in their cabinet from 2013, 2015 and 2018.
Last season, RBNY snuck into the play-offs on Decision Day but lost in extra time to Philadelphia Union in the first round.
Now into his second season at the helm, Gerhard Struber will want better from his players.
In the off-season, Daniel Royer, Issiar Dramé, Andrew Gutman and Mathias Jørgensen have all departed, but their squad is certainly stronger.
$1.2 million was paid to Inter Miami for Lewis Morgan while Luquinhas has come in from Polish champions Legia Warszawa.
Cade Clark will also remain in the Big Apple for 2022 after RB Leipzig extended his loan period for another 12 months.
The Red Bulls should make the play-offs this year but, in the more immediate future, will they win at PayPal Park?
- 101 Great Goals may earn commission from links on this page. Our content is always original. Note that all of our reviewers are compensated for contributing content to 101 Great Goals. Learn more.