New York Red Bulls have won their last two meetings with Portland, winning 4-0 in New Jersey and then 2-0 in Oregon. The Timbers have won just one of five visits to Harrison.
Both teams to score is 4/5.
Both teams to score and over 2.5 goals is 5/4.
New York Red Bulls to win and over 2.5 goals is 13/10.
Patryk Klimala is 9/2 to break the deadlock and 13/8 to add to last weekend's brace with a goal here.
New York Red Bulls are breaking records on the road this season, now needing to improve their home form as they bid for a fourth Supporters' Shield.
Last weekend, RBNY found themsleves a goal down to Chicago Fire, before the game was delayed by around 90 minutes due to heavy rain in Illinois.
When play resumed, Patryk Klimala's late brace, including a stoppage time penalty, saw the Red Bulls snatch a 2-1 victory.
This means RBNY have started an MLS season with five away wins out of five, matching the record held by LA Galaxy, set in 1998.
If they're to break that long-standing record, they'll have to beat current leaders of the east Philadelphia Union in Pennsylvania next Saturday.
Before then, Gerhard Struber's team are seeking to win a home game for the first time this season, having taken just two points from four outings in Harrison.
Can New York RB claim three points and, potentially, end the night top of the Eastern Conference?
Over in the west, last season's MLS Cup Finalists Portland Timbers are languishing down in tenth place.
Their underwhelming start to the season continued last weekend with a 2-0 defeat at Dick's Sporting Goods Park to Colorado Rapids.
So, Giovanni Savarese's team have only won two of ten fixtures so far, most recently beating Vancouver a month ago.
Portland haven't finished below the play-off line since 2016, but that's where they currently find themselves.
Will New York end their Red Bull Arena hoodoo by claiming three points?
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