This match sees MLS’ most successful club take on the reigning Supporters’ Shield winners.
However, both face a real fight to ensure they end up above their respective play-off lines.
LA Galaxy were last in action on Friday night, playing out a 3-3 thriller with Seattle Sounders.
Javier Hernández and then Víctor Vázquez had the hosts 2-0 up and cruising, only for Seattle to completing turn the game around with three goals in 20 minutes.
So, the Galaxy required a stoppage time penalty from Dejan Joveljić to salvage a draw.
This is the Serbian’s seventh goal as a substitute this season, the most from an LA player in one year.
As a result of this victory, Greg Vanney’s team begin the weekend above the play-off line, but only on goal difference.
Over in the east, New England Revolution were demolished 4-0 at Stade Saputo by Club de Foot Montréal last weekend.
This is the Revs biggest defeat since 2019 and ends a five-match unbeaten streak.
So, with eight games to go, including three successive home fixtures, Bruce Arena’s team needs points to make sure they’re invited to the play-off party.
Who will win this crucial clash in Foxborough?