FC Dallas, surprisingly, are unbeaten in 11 meetings with New England, winning nine of these matches. The Revs though have lost just two of their last 18 regular season home games.
So, New England Revolution to win is 4/7.
New England Revs to win and both teams to score NO is 7/4.
Adam Buska is 7/2 to break the deadlock and 20/21 to net anytime.
After a decent point on the road in the season's opening weekend, New England Revolution will be aiming for all three this time as they return to Massachusetts.
Last weekend, the Revs drew 2-2 with last season's Western Conference champions Portland Timbers at Providence Park.
Brandon Bye opened the scoring before new signing Sebastian Lletget thought he'd won it, only for Portland to equalise with a late bicycle-kick.
Nevertheless, that is a decent way to start 2022 for the 2021 Supporters' Shield winners.
Bruce Arena's team will certainly be eyeing up more silverware this year, possible even the biggest club trophy the region has to offer?
Next up, they'll face Liga MX giants Pumas U.N.A.M. in the CONCACAF Champions League quarter-finals; the first leg in Foxborough is on Wednesday.
Before then, will New England claim three points?
FC Dallas meantime also enjoyed a draw to kick off their MLS campaign.
Nico Estévez's side drew 1-1 with Toronto FC last weekend in a cross-conference affair at Toyota Stadium.
Jáder Obrian tapped in the opener, set up by $2 million signing Paul Arriola, but it finished all square in Frisco.
Dallas finished 11th in the Western Conference last season but there were certainly signs they can improve on that and make the play-offs.
Having said that, New England should be too strong at Gillette Stadium, even if they are distracted by Wednesday's huge clash.
- 101 Great Goals may earn commission from links on this page. Our content is always original. Note that all of our reviewers are compensated for contributing content to 101 Great Goals. Learn more.