These two sides have only ever met five times with LA winning three and Orlando two. Both encounters in Carson have produced home wins, 4-2 and 4-3, with the Galaxy also winning their last clash 1-0 in Florida.
LA Galaxy to win this one too is 5/6.
LA Galaxy to win and both teams to score NO is 9/4.
Javier Hernández has already secored twice in three appearances this season. He is 11/4 to break the deadlock and 4/5 to add to his tally.
Will LA Galaxy rediscover that winning feeling?
Greg Vanney's side began the campaign with back-to-back wins, both 1-0, beating champions NYCFC and then Charlotte FC in North Carolina.
However, last weekend, the Galaxy found Lumen Field a tougher venue to visit.
Star men Javier Hernández and Douglas Costa were both on target, the latter a deflected free-kick, but Seattle Sounders won it with a 72nd minute header.
Nevertheless, two wins out of three isn't a bad start for the side who've failed to make the play-offs in four of the last five seasons.
Will they claim a second home victory of 2022 here?
Orlando City meanwhile suffered the indignity of losing to Major League Soccer's worst team last weekend, at home as well.
FC Cincinnati had lost a record-breaking 14 consecutive MLS matches before rocking up at Exploria Stadium and leaving 2-1 winners.
In fairness, Orlando did have 18 shots, six on target, but Júnior Urso's first half equaliser was in vain.
So, Óscar Pareja's men have four points on the board having beaten Club de Foot Montréal 2-0 and then drawn 0-0 with Chicago Fire in Illinois.
Anything other than a home win would be a surprise at Dignity Health Sports Park.
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