Inter Miami, by virtue of not playing, dropped out of the play-off places last weekend, making this fixture vitally important for the visitors.
When the Herons were last in action, 11 days ago, they were beaten 2-0 by Columbus Crew at Lower.com Field.
That made it back-to-back defeats for Phil Neville’s team, also beaten 3-1 by RBNY, despite being unbeaten in five beforehand.
So, with just six games to go, Inter Miami need wins if they’re to qualify for the play-offs for the first time ever.
Chicago Fire meanwhile have only featured in the post-season once since 2012, a statistic that isn’t going to change anytime soon.
Ezra Hendrickson’s team have drawn their last two matches, both 0-0, first at New England and then in Columbus last weekend.
Overall, the Fire are winless in five, despite accumulating 13 points from their five previous outings.
So, Chicago sit 13th in the east, seven points below the play-off line, meaning their season is petering out once again.
In their first match at SeatGeek Stadium since 2019, Soldier Field is unavailable, will Chicago’s winless streak come to an end?