Recommended bets
Hartlepool have only won one of their last eight matches against Tranmere, including a 1-0 reverse at Prenton Park in September.
So, Tranmere Rovers to win and both teams to score NO is 3/1.
None of their last 11 encounters have witnessed more than two goals. Under 2.5 goals again is 8/13.
Match preview
Will Tranmere Rovers stay on track for promotion to League One?
The Super White Army suffered a rare setback on Saturday, losing 1-0 at Walsall, which was only their second defeat since 13 November.
Thus, Micky Mellon's men remain second five points clear of Exeter City in fourth.
Hartlepool United meanwhile are back in the Football League this season and are well on course to cement their place in this division.
Pools beat Crawley Town 1-0 at the weekend, Omar Bogle with the winner, so Graeme Lee's side have now secured back-to-back wins for the first time since October.
This leaves Hartlepool 15th, 11 points clear of any danger.
Will the home side be too strong at Prenton Park?
Hartlepool United team news
Teenager Joe Grey was Hartlepool's hero in the FA Cup, scoring the winner against Blackpool, and has been a regular in the side ever since.
Omar Bogle, after getting the winner at the weekend, and top scorer Luke Molyneux will form the attack.
Tranmere Rovers team news
Ross Doohan has established himself as the number one goalkeeper at Tranmere since joining on loan from Celtic, starting 25 successive league games.
Lee O'Connor, usually a centre-back, has also come in from the Scottish Premiership leaders but has been utilised in midfield at Prenton Park.
FA Cup winner Callum McManaman could return to the XI after sitting on the bench at Walsall on Saturday.
League Two table:
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