Real Betis have actually won at the Bernabéu in both 2017 and 2019 but, before that, their last victory at the venue was in 1998. The last 22 matches between these two have produced 76 goals with both teams scoring in 14 of them.
Both teams to score is 1/2.
Both teams to score and over 2.5 goals is 8/11.
Real Madrid to win and over 2.5 goals is 9/4.
Karim Benzema has scored eight goals in his last 15 appearances against Real Betis. He is 3/1 to break the deadlock and 4/6 to add to his tally.
It's already been an historic season for Real Madrid but it could yet be one of the best in their entire history.
20 days ago, los Blancos hammered Espanyol 4-0, thereby confirmed they'd won La Liga so were duly presented with the trophy afterwards.
Since, their league form has been mixed, losing to Atlético Madrid in the derby, hammering Levante 6-0 before a 1-1 draw at Cádiz.
In the latter, back-up goalkeeper Andriy Lunin was the hero, saving a penalty to preserve the point after Mariano had broken the deadlock.
But, all of this is irrelevant really because Carlo Ancelotti is merely using these inconsequential games as preparation for the Champions League Final.
Next Saturday, they'll take on Liverpool at the Stade de France, so have eight days preparation time, two more than the Reds.
Only three times previously, in 1957, 1958 and 2017, have Real won La Liga and the European Cup in the same season.
Also, having lifted the Supercopa de España in January, they could win La Liga, the Champions League and another trophy in the same season for just the third time.
Real Betis meanwhile are also in party mood as, last month, they won the Copa del Rey, claiming major silverware for the first time in 17 years.
Manuel Pellegrini's side were unable to put the icing on the cake by finishing in the top four though with their hopes of that ending last weekend.
This is despite the fact Béticos have won their last two La Liga games, beating Valencia 3-0 and Granada 2-0; Juanmi with a brace in the latter.
So, los Verdiblancos remain fifth which is a respectable finish, along-with the small matter of major silverware.
Will Real Betis play the role of party poopers at Estadio Santiago Bernabéu?
Real Madrid team news
Carlo Ancelotti faces a selection dilemma doesn't he?
On the one hand, he should rest all of his key players with the Champions League Final just eight days away.
Conversely, he should put out his strongest XI to fine-tune as that massive game in Paris is over a week away.
Three of the first-choice back four is set, featuring Dani Carvajal, Éder Militão and Ferland Mendy.
However, David Alaba's fitness and form means Nacho will start here, hoping to stake a claim.
Also, Jesús Vallejo could start a fifth consecutive La Liga game, although he isn't in contention for next weekend.
Obviously, Casemiro, Luka Modrić and Toni Kroos are the first picks in midfield.
They'll all start against Liverpool, but any number of Eduardo Camavinga, Dani Ceballos and Federico Valverde could start this one.
Valverde might be on the right-hand-side next weekend, alongside Vinícius Júnior and Karim Benzema.
Meanwhile, this'll be Gareth Bale's farewell to the Bernabéu; it'll be intersting to see the reception he gets having won 15 trophies with the club.
Isco is injured but Eden Hazard, Marco Asensio, Rodrygo, Luka Jović and Mariano Díaz are all in contention.
Real Betis team news
As for the visitors, this is the 56th and final game of their hectic season, so they have nothing to lose.
Top scorer Juanmi took his season's tally to 20 last weekend so will be looking for another one here.
Borja Iglesias and Nabil Fekir will complete the attack.
Joaquín, who'll celebrate his 41st birthday in July, isn't going to retire but will also be hoping to feature.
However, this is set to be Héctor Bellerín's final game in a Betis shirt; he was in tears last weekend having won the Copa with his boyhood club.
La Liga table:
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