New York Red Bulls 2 – Philadelphia Union 1 (MLS, April 24, 2010) Salou Ibrahim got the Red Bulls on the board with a header early in the second half, but they were soon pegged back when in-form Union striker Sebastien Le Toux slide in the equaliser. Juan Pablo Angel converted a penalty in the 67th minute to lead the Red Bulls to their fourth win in their opening five matches of the season.
Chicago Fire 2 – Houston Dynamo 0 (MLS, April 24, 2010)
Columbus Crew 1 – Real Salt Lake 0 (MLS, April 24, 2010)
New England Revolution 1 – Colorado Rapids 2 (MLS, April 24, 2010) Colorado stormed to victory thanks to long range efforts from Mehdi Ballouchy and Pablo Mastroeni on either side of half time, with New Englandâ€™s Marko Petrovic doing the only damage for the home side.
Kansas City Wizards 0 – Los Angeles Galaxy 0 (MLS, April 24, 2010)
Chivas USA 3 – San Jose Earthquakes 2 (MLS, April 24, 2010)