Nacional Montevideo 0 – Argentinos Juniors 1 (Copa Libertadores, March 2, 2011) Nacional gifted Argentinos their goal in the 22nd minute when keeper Burian collided with Marques as they went for a long ball into the box and striker Franco Niell netted the loose ball for his third goal of the competition.
Santos 1 – Cerro Porteno 1 (Copa Libertadores, March 2, 2011) Argentine striker Roberto Nanni equalised with a penalty in added time for his fifth goal in the competition after Brazil midfielder Elano had given Santos the lead from the spot early in the second half.
Club America 1 – Fluminense 0 (Copa Libertadores, March 2, 2011) Substitute striker Daniel Marquez scored the only goal at the Azteca in the 71st minute, seven minutes after coming on.
Deportes Tolima 0 – Cruzeiro 0 (Copa Libertadores, March 2, 2011) Goalkeeper Fabio saved a penalty as Libertadores Cup favourites Cruzeiro of Brazil drew 0-0 away to Deportes Tolima.
San Luis 1 – Once Caldas 1 (Copa Libertadores, March 2, 2011) Wason Renteria fired Once Caldas ahead early on but Michael Arroyo ensured it finished all square when he equalised from a free-kick.