Botafogo 1 – Cerro Porteno 3 (Agg. 2-5) (Copa Sudamericana, November 4, 2009) The Paraguayans stole in front 11 minutes after the interval, when Jorge Nunez’s header beat Jefferson. Andre Lima equalised in the 73rd minute but Alessandro left Botafogo down to 10 men two minutes later when he was sent off for a heavy challenge on Luis Cardozo. Botafogo needed to score to take the tie to penalties, but Julio Irrazabal increased Cerro’s aggregate lead to 4-2 with three minutes remaining. In stoppage-time, Luis Caceres finished another counter-attack to consolidate the victory for Cerro.
San Lorenzo 0 – River Plate 1* (Agg. 1-1) (Pens. 6-7) (Copa Sudamericana, November 4, 2009) San Lorenzo fell behind 46 seconds into the second half when Richard Porta profited from Kily Gonzalez’s mistake and beat Pablo Migliore with a left-footed shot. In the shoot-out, the first four misses did not prove decisive but the fifth did, as Pablo Pintos saw his effort saved by River goalkeeper Luciano Dos Santos.