A massive, potentially decisive, clash for both at Camp Nou.
Eight nights ago, Inter prevailed at San Siro, thanks to Hakan Çalhanoğlu’s stunning strike in first half stoppage time.
Safe to say Barcelona left Milan furious; Pedri saw an equaliser chalked off, before Denzel Dumfries was not penalised for handball.
So, despite the fact there are two matchdays to go after this one, defeat to the Catalan would could be curtains.
Barça were eliminated in the Champions League group stages for the first time since 2000 last season, but are on the brink of a repeat.
If Inter leave Catalonia victorious, they and Bayern will be guaranteed a knockout stages spot, due to the second tiebreaker being head-to-head.
Even if this game ends in a draw, all I Nerazzurri would need is to beat Viktoria Plzeň at home to get through.
In summary, this is simply must win for Barcelona and, if they do, it would then be game on.
Who will claim three simply priceless point?