De Paul, Rodrigo
Man City managed to keep a clean sheet in the first-leg.
They have now kept six clean sheets in their last nine matches.
Atletico Madrid are also coming off the back of a 1-0 defeat to Mallorca.
De Bruyne has been on fire in front of goal over recent weeks.
The midfielder has six goals in his last six appearances in all competitions.
He netted the only goal of the game in the first-leg.
Match preview: Atletico Madrid vs Manchester City
Atletico Madrid suffered a shock defeat over the weekend in La Liga.
Atleti were beaten by Mallorca as they suffered their first defeat in 7 matches.
Simeone’s team have now dropped back into 4th place and are just a point ahead of Real Betis.
In the Champions League, they trail Man City by one goal following their 1-0 defeat in Manchester last week.
They were unable to beat Man United at Wanda Metropolitano in the last round but they must beat City on Wednesday to make it into the semis.
Manchester City held to draw by Liverpool
Manchester City’s top of the table clash with Liverpool ended with a draw.
City and the Reds drew 2-2 at the Etihad with Klopp’s side twice coming from behind.
Guardiola’s men will walk away from the clash the happier of the two sides as they remain top.
Just a point separates the two teams with 7 games remaining.
City will now turn their attention back to the Champions League and to defending their 1-0 lead in Madrid.
De Bruyne scored the only goal of the game in the first-leg.
Atletico Madrid team news
Atletico are expected to remain without both Renan Lodi and Hector Herrera.
The duo missed the club’s defeat against Mallorca on the weekend.
Manchester City team news
Ruben Dias is back in contention following a thigh injury.
The defender is back in training but unlikely to feature in Madrid.
Cole Palmer remains sidelined with an ankle injury.
Atletico Madrid vs Sevilla FC - 1:1
Elche CF vs Atletico Madrid - 0:2
Atletico Madrid vs Real Madrid - 1:0
Athletic Bilbao vs Atletico Madrid - 2:0
Atletico Madrid vs Granada CF - 0:0
|Latest match form, last 5 games:||
West Ham United vs Manchester City - 2:2
Wolverhampton Wanderers vs Manchester City - 1:5
Manchester City vs Newcastle United - 5:0
Real Madrid vs Manchester City - 3:1
Leeds United vs Manchester City - 0:4
|May 15, 2022||LaLiga 21/22||Atletico Madrid||1 - 1||Sevilla FC|
|May 11, 2022||LaLiga 21/22||Elche CF||0 - 2||Atletico Madrid|
|May 8, 2022||LaLiga 21/22||Atletico Madrid||1 - 0||Real Madrid|
|April 30, 2022||LaLiga 21/22||Athletic Bilbao||2 - 0||Atletico Madrid|
|April 20, 2022||LaLiga 21/22||Atletico Madrid||0 - 0||Granada CF|
|May 15, 2022||Premier League 21/22||West Ham United||2 - 2||Manchester City|
|May 11, 2022||Premier League 21/22||Wolverhampton Wanderers||1 - 5||Manchester City|
|May 8, 2022||Premier League 21/22||Manchester City||5 - 0||Newcastle United|
|May 4, 2022||UEFA Champions League 21/22||Real Madrid||3 - 1||Manchester City|
|April 30, 2022||Premier League 21/22||Leeds United||0 - 4||Manchester City|
|Atletico Madrid||Manchester City|
|25||Shots on goal||70|
|37||Shots off goal||54|
|34%||Average ball possession||47%|
|3||Shots on post||0|
|7||Goals by foot||24|
|2||Goals by head||4|
|0||Shots on bar||3|
|Atletico Madrid||Manchester City|
|0||Average Goals Scored||0.5|
|April 13, 2022||UEFA Champions League 21/22||Atletico Madrid||0 - 0||Manchester City|
|April 5, 2022||UEFA Champions League 21/22||Manchester City||1 - 0||Atletico Madrid|
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What time is kick off between Atletico Madrid vs Manchester City?
19:00, Wednesday 13 April 2022