Real Madrid travel to the Mestalla with a 2-0 lead from the first leg and for their third encounter with Valencia in a week. Kick off is at 20.30 GMT on January 23, 2013.
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Having smashed seven goals past Valencia in two games, it would be a major surprise if Jose Mourinho’s side did anything but blitz their hosts on Wednesday evening.
Valencia will be without star striker Roberto Soldado due to a thigh problem which makes their challenge even harder. A positive is that Sergio Canales could make a return from long term injury against his former club.
Mourinho has been tipped to make changes with the likes of Jose Callejon and Ricardo Carvalho suggested as possible players to start the match.
Kaka though is not part of the squad as rumours continue to swirl of a return to AC Milan during the current transfer window.
Can Valencia get back into this tie? Unlikely, but if they could grab the opener anything could happen.