Olympiakos: Roberto, Manolas, Marcano, Salino, Holebas, N’Dinga, Maniatis, Dominguez, Fuster, Campbell, Olaitan.
Javier Saviola is out for the Greeks.
Manchester United: De Gea; Rafael, Smalling, Vidic, Evra; Carrick, Fletcher; Valencia, Rooney, Young; Van Persie.
Manchester United defenders Phil Jones and Jonny Evans have been ruled out of the last 16 first leg.
Some essential stats to help with online betting:
Manchester United have won their four previous matches with Olympiakos, all in the Champions League (12 goals for, 2 against).
Olympiakos have won six of their last eight home games in the Champions League and they have scored in those eight games.
Manchester United have only conceded three goals in the Champions League this season, the best defensive tally alongside Atletico Madrid and Chelsea.
Manchester United have kept a clean sheet in each of their last four Champions League games, the best current run in the competition.
Wayne Rooney has scored two goals and delivered three assists in five Champions League games this season.