Boca Juniors 2 – San Lorenzo 0 (Clausura, April 25, 2010) Boca Juniors scored a fourth win of their disappointing campaign, with Matias Gimenez and Martin Palermo securing a 2-0 win against San Lorenzo.
Atletico Tucuman 2 – Rosario Central 2 (Clausura, April 25, 2010) Luis Rodriguez got both of the goals for Tucuman, who had Rodrigo Herrera red carded, with Emilio Zelaya and Milton Caraglio twice equalising.
Racing Club 2 – Banfield 0 (Clausura, April 25, 2010) Racing Club beat Banfield with goals from Matias Martinez and Claudio Bieler in the last 15 minutes.
Argentinos Juniors 3 – Gimnasia La Plata 1 (Clausura, April 25, 2010) Nestor Ortigoza opened the scoring for the hosts with a 26th-minute penalty before Lucas Castro equalised just seconds after coming on in the 67th minute. Ismael Sosa restored the lead two minutes later and Santiago Raymonda made it three in the closing minutes.